谢三磊

职称/职务

讲师

政治面貌

中共党员

研究方向

动物源性食品安全

E-mail

xiesanlei@163.com

学术、技术组织任职/头衔

受教育经历

2007.9-2011.7，河南科技大学动植物检疫专业，获理学学士学位

2011.9-2014.6，甘肃农业大学基础兽医学专业，获农学硕士学位

2014.9-2019.9，中国农业大学基础兽医学专业，获农学博士学位

工作学习经历

2019.7-2023.11 西南大学动物医学院讲师

2023.11-至今河南科技大学动物科技学院动物医学院讲师

讲授课程

《药物化学》、《抗菌药物治疗学》

科研项目

1、 国家自然科学基金青年项目，321026331，金刚烷胺B细胞受体CDR3免疫组库动态演化及分子识别机制研究，2022.1-2024.12，30万元，主持

2、 重庆市自然科学基金面上项目，肺炎链球菌磷壁酸调控宿主炎症小体激活的相关机制研究，主持

代表性论文

[1] Wang, Zile; Ma, Qiang;   Zheng, Pimiao; Xie, Sanlei. Generation of broad-spectrum recombinant antibody   and construction of colorimetric immunoassay for tropane alkaloids:   Recognition mechanism and application,Journalof Hazardous Materials,September 2023, 459, 132247.

[2] Sanlei   Xie, Yuehong Yue, Guoyang Xu. In situ formed carbon   nanoparticles enables colorimetric and fluorometric dual-mode immunoassay   detection of amantadine in poultry foodstuffs, Microchemical Journal, May   2023, 192, 108895.

[3] Tao, Qi, Xu, Dongyi,   Jia, Kaixiang, Cao, Xinrui, Ye, Chao, Xie, Sanlei, et al. NLRP6   Serves as a Negative Regulator of Neutrophil Recruitment and Function During   Streptococcus pneumoniae Infection, FRONTIERS IN MICROBIOLOGY, May 2022, 13,   898559.

[4] Sanlei Xie, Jianyi Wang,   Xuezhi Yu, et al. Site-directed mutations of anti-amantadine scFv antibody by   molecular dynamics simulation: prediction and validation, JOURNAL OF   MOLECULAR MODELING, February 2020, 26, 49, pp 1–9.

[5] Sanlei Xie, Kai Wen,   Tao Peng, et al. Magnetic-assisted biotinylated single-chain variable   fragment antibody based immunoassay for amantadine detection in chicken,   Analytical and Bioanalytical Chemistry, September 2018, 410, 24, pp   6197–6205.

[6] Sanlei Xie, Kai Wen,   Sihan Wang, Haiyang Jiang, et al. Quantitative and rapid detection of   amantadine and chloramphenicol based on various quantum dots with the same   excitations, Analytical and Bioanalytical Chemistry, 2019, 411:2131– 2140.

[7] Sanlei Xie, Kai Wen,   Tao Peng, et al. A novel variable antibody fragment dimerized by the dHLX   peptide with enhanced affinity against amantadine compared to its   corresponding scFv antibody, Food and Agricultural Immunology, DOI:   10.1080/09540105.2017.1368459.

[8] Huiling Sun, Sanlei   Xie, Xiaofei Li, et al. Selection of Avibacterium paragallinarum Page serovar   B strains for an infectious coryza vaccine, Veterinary Immunology and   Immunopathology, 2018, 199, 77-80.

教材、编著、专著

获奖

1.2022年，《兽医药理学》重庆市一流课程(排名5)，重庆市教育局，

新药、新品种

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