文凤云

文凤云（1979-），女，陕西咸阳人。中共党员，博士，副教授，硕士生导师。河南省青年骨干教师，河南省女职工先进个人，河南科技大学优秀教师。主要从事动物生物化学课程的教学与科研工作，主要研究方向为功能基因表达及脂质代谢调控。主持国家自然科学基金项目2项,参与了国家973、863、国家转基因专项等多个项目的研究工作。在《International Journal of Biochemistry and Cell Biology》，《Biochemical and Biophysical Research Communications》，《中国生物化学与分子生物学报》，《中国农业科学》等国内外期刊发表学术论文30余篇。主编及参编著作6部。

项目：

1、国家自然科学基金联合基金项目，U1804118，猪抵抗素通过线粒体数量调控肌源性MSCs成脂分化与肌内脂肪沉积，48万元，主持。

2、国家自然科学基金，31301940、抵抗素诱导猪脂肪异位沉积中miR-34a的调控机制研究， 22万元，主持。

3、国家自然科学基金，31101779、脂肪源性干细胞向血旺细胞分化过程中的MicroRNA调控研究， 21万元，参加。

4、国家自然科学基金，31100886、肺鱼免疫球蛋白重链基因位点结构及多样性机制研究， 21万元，参加。

论文:

Fengyun Wen, Chaoqing An, Xiaotian Wu, Yi Yang, Jingjing Xu, Yasong Liu, Chunming Wang, Leitong Nie, Hubin Fang, Zaiqing Yang. MiR-34a regulates mitochondrial content and fat ectopic deposition induced by resistin through the AMPK/PPARα pathway in HepG2 cells. International Journal of Biochemistry and Cell Biology.2018,94:133-145.

Wen F, Zheng J, Yu J, Gao M, Gao S, Zhou Y, Liu J, Yang Z. Macrophage migration inhibitory factor in the regulation of myoblast proliferation and differentiation. Biosci Biotechnol Biochem. 2016, 80(7):1313-20.

FengyunWen, Bin Li, Chunyan Huang, Zhiguo Wei, Yingying Zhou, Jianyu Liu, Haiwei Zhang. MiR-34a is involved in the decrease of ATP contents induced by resistin through target on ATP5S in HepG2 cells. Biochemical Genetics, 2015,53（11-12）：301-309.

Fengyun Wen, Lei Zhou, Xiaotian Wu, Shengnan Xia, Chao Sun, Zaiqing Yang, Characterization of miRNA and mRNA expression profiles in liver of resistin-treated mice by microarray. Acta Endocrinologica (Buc), 2015,11: 284-293.

Fengyun Wen, Haiwei Zhang, Chen Bao, Mengshi Yang, Nan Wang, Jie Zhang, Yajie Hu, Xi Yang, Jinjing Geng, Zaiqing Yang, Resistin increase ectopic deposition of lipids through miR-696 in C2C12 cells, Biochemical Genetics, 2015, 53(4-6):63-71.
    Fengyun Wen, Yi Yang, Dan Jin, Jun Sun, Xiaoling Yu, Zaiqing Yang.MiRNA-145 is involved in the development of resistin-induced insulin resistance in HepG2 cells. Biochemical and Biophysical Research Communications, 2014, 445: 517-523.